From that last shot, we can see that there is only about an inch of clearance between the fan and the side of the case. This could lead to breathing issues. In anticipation of this, I cut a 120mm fan hole right over the heatsink. However, I will test with a solid side just to see whether it was necessary.
Well, despite those difficulties, this beast is installed and ready to go. We now know that it is quite possible to do an in-case install. I even uninstalled it just to make sure that would be possible too. In a smaller case, things could get quite cramped; however I believe that it is easier due to the fact that you don't have to deal with motherboard removal and reinstallation. Now let's see whether this labor was worth it!